GitHub

Pharma Pipeline Intelligence MCP

Competitive pharmaceutical pipeline intelligence for AI agents. Search clinical trials, analyze FDA approvals, detect adverse events, and track drug recalls. Pharma Pipeline Intelligence MCP is an MCP ...
Nature

In silico docking yields small molecule negative allosteric modulators targeting the core of Frizzled 7

Here, we wanted to specifically explore possibilities to target the 7TMD with small-molecule modulators. For this, we utilized docking calculations to a cryo-EM structure of the 7TMD of a G ...
GitHub

XML -- XML 1 - Find the Score

You are given a valid XML document, and you have to print its score. The score is calculated by the sum of the score of each element. For any element, the score is equal to the number of attributes it ...
C&EN

CANDID-CNS: AI Unlocks Stereochemistry and Beyond Rule of 5 to Predict CNS Penetration of Small Molecules

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Non-Commercial (NC): Only non-commercial uses of the work are permitted. Neuroscience ...
C&EN

Caprolactam Cocrystals: Bridging Virtual Screening to Experimental Solid-State Forms and Stability

Institute of Pharmacy, Pharmaceutical Technology, University of Innsbruck, Innsbruck 6020, Austria Christian Doppler Laboratory for Advanced Crystal Engineering Strategies in Drug Development, ...
Nature

Structures of Teneurin adhesion receptors reveal an ancient fold for cell-cell interaction

Teneurins are ancient cell–cell adhesion receptors that are vital for brain development and synapse organisation. They originated in early metazoan evolution through a horizontal gene transfer event ...