Scientists Create Tiny “Mini Livers” That Could One Day Replace Liver Transplants

Engineered tissue grafts could help perform key liver functions and benefit thousands of people living with liver failure.

Fish-inspired sensor tracks how human heart tissue responds to disease and treatment

Engineers have developed a new way to monitor how tiny lab-grown human heart tissues beat—by effectively "listening" to the ...

Injectable silk-kudzu hydrogel achieves complete wound closure in laboratory tests

Researchers at the Terasaki Institute for Biomedical Innovation have developed an injectable hydrogel, a water-based gel ...
katv

UAMS brings incision-free histotripsy ultrasound treatment for liver tumors to Arkansas

LITTLE ROCK, Ark. (KATV) — A new cancer treatment that does not require a single incision is now available in Arkansas, giving some patients with liver tumors another option beyond surgery, radiation ...
Frontiers

Glutathione peroxidase 2 expression in human tumors: a tissue microarray study on 18,555 tumors

G, grade; pN, pathologic lymph node status; pT, pathologic tumor stage; L, lymphatic invasion status; V, blood vessel invasion status; RAS, rat sarcoma virus; BRAF, v ...
Medscape

Prediabetes Tied to Weight Regain After Bariatric Surgery

Prediabetes may leave a molecular “footprint” on fat tissue that makes maintaining weight loss after bariatric surgery difficult, new research showed. “Our study shows that prediabetes is associated ...
News Medical

Prediabetes leaves lasting fat tissue changes after bariatric surgery

Prediabetes may leave a lasting molecular "footprint" on adipose (fat) tissue which appears to make maintaining weight loss after bariatric surgery more difficult, according to new research being ...
gut.bmj

Epigenetic modification of MiR-429 promotes liver tumour-initiating cell properties by targeting Rb binding protein 4

3 Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China 4 Changzheng Hospital, Second Military Medical University, Shanghai, China Correspondence to Dr Hongyang ...
gut.bmj

DNA-methylation signature accurately differentiates pancreatic cancer from chronic pancreatitis in tissue and plasma

Objective Pancreatic ductal adenocarcinoma (PDAC) is a lethal malignancy. Differentiation from chronic pancreatitis (CP) is currently inaccurate in about one-third of cases. Misdiagnoses in both ...
The Lancet

Integrating microarray-based spatial transcriptomics and single-cell RNA-sequencing reveals tissue architecture in esophageal squamous cell carcinoma

aDepartment of Thoracic Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ...
C&EN

Optimization of an Antibody Microarray Printing Process Using a Designed Experiment

Center for Applied NanoBioscience and Medicine, College of Medicine, University of Arizona, Phoenix, Arizona 85004, United States Department of Basic Medical Sciences, The University of Arizona, ...
Frontiers

Gene Expression Profiles Analyzed Using Integrating RNA Sequencing, and Microarray Reveals Increased Inflammatory Response, Proliferation, and Osteoclastogenesis in Pigmented ...

Pigmented villonodular synovitis (PVNS) is a rare condition that involves benign proliferation of the synovial tissue and is characterized by severe joint destruction and high recurrence even after ...