Alternative splicing (AS) plays a critical role in generating cellular transcriptomic heterogeneity. While single-cell RNA sequencing (scRNA-seq) has become a standard approach for exploring this ...
Esophageal carcinoma ranks as the sixth leading cause of cancer-related mortality globally, with esophageal squamous cell carcinoma (ESCC) being particularly prevalent among Asian populations.
Alternative pre-mRNA splicing is critical for post-transcriptional regulation of gene expression, during which particular exons from the same pre-mRNA might be excluded, included or modified to ...
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