Minimally disruptive genetic code expansion enables faithful, site-specific labeling of G3BP1 and TDP-43, revealing native stress granule dynamics and ALS-linked protein behavior in live cells.
In the study of bacteria, a longstanding dogma has held that two molecular machines—RNA polymerase, which leads the way in transcribing DNA into RNA, and ribosomes, which bring up the rear translating ...
In cancer research, one person's junk is increasingly becoming another person's treasure. Scientists have now uncovered new evidence showing how recently evolved "junk DNA" genetic elements can become ...
In cancer research, one person's junk is increasingly becoming another person's treasure. Scientists have uncovered new evidence showing how recently evolved "junk DNA" genetic elements can become ...
The site-specific incorporation of unnatural or non-canonical amino acids (ncAAs) into proteins is a universally important tool for systems bioengineering at the interface of chemistry, biology, and ...
The RNA world hypothesis proposes that early life was based on RNA, which subsequently devolved the storage of information to more stable DNA, and catalytic functions to more versatile proteins.
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