Abstract: Over the last 25 years, the multiple sequence alignment (MSA) problem has attracted the attention of biologists because it is one of the major techniques used in several areas of ...

One of the challenges presented by the new sequencing technology is the so-called 'read mapping' problem. Sequencing machines made by Illumina of San Diego, Applied Biosystems (ABI) of Carlsbad, ...

The purpose of swarm is to provide a novel clustering algorithm that handles massive sets of amplicons. Results of traditional clustering algorithms are strongly input-order dependent, and rely on an ...

Expression-based systems that use only native alignments tend to produce exon-intron structures that are quite accurate. Their primary limitation is that there are many genomes for which little or no ...