Piecing the puzzle of how proteins fit together: Simpler model outperforms leading methods

How the proteins in our bodies bind together to form protein complexes plays a critical role in numerous cell functions—staving off diseases, for instance, or transporting ions across cell membranes.

A.I.’s First Big Math Breakthrough Is Not What It Seems

Last month, OpenAI announced that its latest version of ChatGPT had solved a major math problem, one that had stumped experts ...
Nature

Tsang’s resolution enhancement method for imaging with focused illumination

A widely tested approach to overcoming the diffraction limit in microscopy without disturbing the sample relies on substituting widefield sample illumination with a structured light beam. This gives ...
C&EN

Development of Receptor Desolvation Scoring and Covalent Sampling in DOCK 6: Methods Evaluated on a RAS Test Set

NCI RAS Initiative, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc., P.O. Box B, Frederick 21702, Maryland, United States ...
Nature

Research on X-ray nondestructive defect detection method of tire based on dynamic Snake Convolution YOLO model

Tire X-ray nondestructive testing before leaving the factory is crucial for driving safety. Given the complexity of tire structures and the diversity of defect types, traditional manual visual ...
Frontiers

FFT-Based Methods for Computational Contact Mechanics

Computational contact mechanics seeks for numerical solutions to contact area, pressure, deformation, and stresses, as well as flash temperature, in response to the interaction of two bodies. The ...
Frontiers

SDN2GO: An Integrated Deep Learning Model for Protein Function Prediction

The assignment of function to proteins at a large scale is essential for understanding the molecular mechanism of life. However, only a very small percentage of the more than 179 million proteins in ...
C&EN

Effects of extracolumn convolution on preparative chromatographic peak shapes

Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to ...