AbbVie Receives Positive CHMP Opinion for Upadacitinib (RINVOQ®) for the Treatment of Adults and Adolescents with Non-segmental Vitiligo

If approved, upadacitinib is expected to be the first systemic medication for patients with non-segmental vitiligo, addressing important treatment needs ...
Quanta Magazine

After 80 Years, Mathematicians Give Famed ‘Erdős Method’ an Upgrade

Decades ago, Paul Erdős used randomness to illuminate the vast and weird world of networks. Now mathematicians are making his ...

Drug peptides defy shape rules, activating receptors without full spiral form

When many of us think about how drugs work in the body, we may first think about how a drug gets into the body, such as a pill versus an injection. In the Gellman Group at the UW–Madison Department of ...

Liquid ripples rewrite 130-year-old biological classic: New reflections on the lock-and-key model

This April, when the spring breeze carried the formal acceptance notice of our paper by the Journal of the American Chemical Society to my desk, my thoughts instantly drifted back to the late Phil ...
Tax Guru

8% Profit Addition Deleted as Revenue cannot Change Consistent Accounting Method: ITAT Delhi

The ITAT Delhi held that the Revenue could not substitute the assessee's consistent method of revenue recognition with the Percentage of Completion Method for only one assessment year. It deleted the ...
IEEE

A Fast Hyperplane-Based Minimum-Volume Enclosing Simplex Algorithm for Blind Hyperspectral Unmixing

Abstract: Hyperspectral unmixing (HU) is a crucial signal processing procedure to identify the underlying materials (or endmembers) and their corresponding proportions (or abundances) from an observed ...
IEEE

A Fully Constrained Linear Spectral Unmixing Algorithm Based on Distance Geometry

Abstract: Under the linear spectral mixture model, hyperspectral unmixing can be considered as a convex geometry problem, in which the endmembers are located in the vertices of simplex enclosing the ...