For most of us, the sense of smell is an integral part of everyday life; it plays a critical role in providing information about our surroundings, alerting us to potential dangers, enhancing our sense ...

Understanding gene expression within the body has been a boon for 21st century biology and therapeutics, but most discoveries that use these technologies only focus on one organ or one small area of ...

In conventional pathology and physiology research, two-dimensional (2D) analysis—observing thinly sliced tissue sections—has been mainstream, making it difficult to comprehensively understand the ...

Scientists have discovered novel molecular mechanisms that contribute to recovery from diabetic kidney disease following bariatric surgery in adolescents with type 2 diabetes and obesity, mechanisms ...

The interplay between cellular metabolism and immune function—immunometabolism—has emerged as a cornerstone of modern pathology (1). Immune cells are not static entities; they continuously adapt their ...

Chronic arterial hypertension causes cerebral microvascular dysfunction and increases dementia risk in aging. However, cognitive health preservation by therapeutic blood pressure lowering alone is ...

University of Kassel, Institute of Biology, Department of Animal Physiology and Neuroethology, Heinrich-Plett-Str. 40, Kassel 34132, Germany University of Kassel, Graduate school: multiscale Clocks, ...

The field of spatial transcriptomics utilizes technologies that map gene expression data to specific cellular locations within tissues. While traditional RNA sequencing methods generate quantitative ...

Introduction: Despite the revealed role of microdosimetry in radiopharmaceutical therapy (RPT), limited knowledge has been established due to the bottleneck in microscale investigations. Although ...