Fritillariae Cirrhosae Bulbus is a valuable and authentic medicinal material widely used in traditional Chinese medicine to treat respiratory diseases. Modern medical research shows that alkaloids, ...

Dams offer numerous benefits to society, but their failure can lead to catastrophic floods, causing severe damage to both people and property. Simulating dam break events and subsequent floods is ...

Point mutations referring to a single base pair change, have a profound effect on the phenotype and play important roles in the variety of diseases (Nasis et al., 2004; Silva et al., 2017; Breveglieri ...

Ras dimerization is critical for Raf activation. Here we show that the Ras binding domain of Raf (Raf-RBD) induces robust Ras dimerization at low surface densities on supported lipid bilayers and, to ...

RAS is mutated in nearly 20% of human cancers and has few direct, efficacious inhibitors. Here, we developed a synthetic protein, JAM20, to discover potential regions on RAS that may be used for ...

How do reservoir sedimentation and appropriate management techniques affect operations of dams and hydroelectric facilities? The authors cover the topic and provide illustrative case studies, ...

1Department of Civil, Environmental and Natural Resources Engineering, Lulea University of Technology, Lulea, Sweden 2College of Engineering, Baghdad University, Baghdad, Iraq. College of Science, ...

Mutations in the Ras family of GTP binding proteins represent one of the most frequently observed genetic alterations in human cancers. We and others have recently demonstrated that expression of Met, ...