Nature

Systematic determination of genetic network architecture

We designed our approach to be systematic and minimally biased by previous knowledge of yeast biology. Our objective was to discover distinct expression patterns (clusters) in mRNA data sets and then ...
University of California, San Francisco

Genetic Test Ranks Risk for Black People Hoping to Donate a Kidney

A UCSF study followed Black kidney donors to see if they faced elevated risks for low kidney function, and found that many ...
eLife

Deciphering interferon functions in avian influenza using receptor knockout models in the natural host

Interferon receptor knockout chickens uncover how type I and III interferons differentially shape avian antiviral immunity and influenza disease outcomes.
Lupus Science & Medicine

Prognostic value of baseline clinical features in SLE: a cluster analysis

Objective SLE is a heterogeneous systemic autoimmune disease with diverse clinical manifestations. We aimed to identify ...
BMJ

Prediction of radiographic progression in rheumatoid arthritis and the role of antibodies against mutated citrullinated vimentin: results from a 10-year prospective study

Objectives: Anti-citrullinated peptide antibodies (ACPAs) are established as useful predictors of radiographic progression in rheumatoid arthritis (RA). The main objective of this study was to test ...
The Lancet

Later eating timing in relation to an individual internal clock is associated with lower insulin sensitivity and affected by genetic factors

eCharité – Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Endocrinology, Diabetes and Nutrition, Campus Benjamin Franklin, ...