This repressive function is aided by competition for genome occupancy between BACH2 and other bZIP transcription factors, such as the AP-1 family member JUN-D 70, 71, 75. T reg cells are high ...
Here the authors perform a genome-wide CRISPR-Cas9 knockout screen to systematically identify and characterize essential and growth-restricting genes in human trophoblast cells. They identify TEAD1 as ...
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