Tumor cells respond and adapt to environmental stresses that facilitate growth in hostile environments, including cytokine-mediated inflammation elicited by antitumor immunity and enhanced by immune ...
Structural changes could be hidden in 2D but revealed in 3D. We therefore used the 4DHiC methodology to reconstruct 3D models from flat Hi-C profiles and obtain 3D spatial measurements 56 (Fig. 4b).
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