Aging, at its most fundamental level, is a molecular process. Chemical marks on the genome shift and lose fidelity over time, ...

Paper in Cloning and Stem Cells shows that animal eggs do not support specific reprogramming toward the normal human embryonic state. Investigators at Advanced Cell Technology (ACTC) have found that ...

Scientists have taken a small but significant step toward testing the idea of reverse aging in humans. Researchers have ...

Cellular reprogramming is the hottest topic in longevity science, with tech titans like Sam Altman investing in it. It's now being tested in humans.

First human receives reverse-aging gene therapy in groundbreaking trial targeting glaucoma, using cellular reprogramming to make aged cells younger.

Human cellular reprogramming to induced pluripotency is still an inefficient process, which has hindered studying the role of critical intermediate stages. Here we take advantage of high efficiency ...

Human-induced pluripotent stem cells (hiPSCs) can differentiate into various tissues, an invaluable characteristic for personalized regenerative medicine, basic and translational research, and drug ...

In a groundbreaking study published in Nature, Australian scientists have resolved a long-standing problem in regenerative medicine. Led by Professor Ryan Lister from the Harry Perkins Institute of ...

Direct neuronal reprogramming offers a promising strategy to generate functional neurons from somatic cells without passing through a pluripotent state. However, the cellular heterogeneity and ...