A compact Cas12f nuclease shows high editing efficiency in human cells, with structural insights enabling an engineered variant potentially suited for future AAV‑compatible delivery.

CRISPR Cas9 gene therapy explained with DNA scissors, hereditary diseases treatment, and designer babies ethical dilemmas ...

Now, following up on that success, a large Chinese collaboration has followed up with a description of an improved gene ...

Scientists have taken an important step toward a gene therapy that could one day turn off the extra genetic material that ...

The ACC has published a scientific statement regarding the use of gene editing therapy for cardiovascular disease.

The CRISPR-Cas gene-editing system has long been the focus of research as a promising tool in genome editing. However, the ...

The last time The Lancet Microbe featured an Editorial on CRISPR was in November 2020, to mark that year’s Nobel Prize in Chemistry, jointly awarded to Emmanuelle Charpentier and Jennifer A Doudna for ...

The rapid evolution of CRISPR/Cas genome editing has redefined the possibilities of cellular and gene therapy, enabling ...

Scientists at the San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), Milan, have found that gene editing using CRISPR-Cas9 in combination with AAV6 vectors can trigger inflammatory and ...